Science

Stevia is an ideal replacement for traditional sugar, especially if you have diabetes or a carbohydrate-controlled diet. That way, you can enjoy sweet foods without dealing with diabetic complications. Unlike normal sugar made of sucrose, stevia contains stevioside. It is a glycoside compound, not a carbohydrate. Table sugar is absorbed into the bloodstream. As stevioside breaks down, the glucose is absorbed in the colon by bacteria.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://facty.com/food/nutrition/10-surprising-benefits-and-risks-of-the-alternative-sweetener-stevia/?style=quick&utm_source=adwords&adid=267723668343&ad_group_id=57749014289&utm_medium=c-search&utm_term=stevia&utm_campaign=FH-USA-Search-Health-Benefits-and-Risks-of-Stevia&gclid=EAIaIQobChMI1v_2gJqCgQMV1gQGAB1JAgLjEAAYAyAAEgL1VvD_BwE

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Pancreatic cancer has an extremely poor prognosis, largely due to a poor record for early detection. Known risk factors for pancreatic cancer include obesity, diet, and diabetes, implicating glucose consumption and regulation as a key player. The role of artificial sweeteners may therefore be pertinent to disease kinetics. The oncogenic impact of artificial sweeteners is a highly controversial area. #Stevia #kombucha #ikombucha_ro #ikombucha
https://www.frontiersin.org/articles/10.3389/fonc.2017.00018/full

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Stevia, a zero-calorie sugar substitute, is recognized as safe by the Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). In vitro and in vivo studies showed that stevia has antiglycemic action and antioxidant effects in adipose tissue and the vascular wall, reduces blood pressure levels and hepatic steatosis, stabilizes the atherosclerotic plaque, and ameliorates liver and kidney damage. The metabolism of steviol glycosides is dependent upon gut microbiota, which breaks down glycosides into steviol that can be absorbed by the host. In this review, we elucidated the effects of stevia’s consumption on the host’s gut microbiota. #Stevia #kombucha #ikombucha_ro #ikombucha
https://www.mdpi.com/2076-2607/10/4/744/htm

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To help offset potential stevia induced gut challenges, support your gut flora with fiber and prebiotics like FOS10 (fructo-oligosaccharides). Increase your intake of beneficial bacteria Lactobacillus and Bifidus to aid in a healthier gut microbiome.
Consider foods and nutrients like cruciferous vegetables (Brussels sprouts, cabbage, broccoli, cauliflower, kale), silymarin, dandelion, resveratrol, curcumin, magnesium, zinc, limonene, B vitamins, and omega-3 oils to help your liver’s glucuronidation pathway.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.bbc.com/mundo/noticias/2013/07/130717_salud_nutricion_stevia_finde_gtg

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Ancestral intake of the raw stevia leaf was extremely limited compared to current exposures of refined stevia found in many manufactured food products. I am a proponent of using foods in their natural, whole form when possible.
Avoid processed refined sugars and foods with added sugars, but rather use raw local honey, blackstrap molasses, real maple syrup, or other natural sugars. Think about it, would your grandmother or great grandmother use something like refined stevia in their made from scratch homemade recipes?
#Stevia #kombucha #ikombucha_ro #ikombucha
https://medlineplus.gov/spanish/druginfo/natural/682.html

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Artificial sweeteners or intense sweeteners are sugar substitutes that are used as an alternative to table sugar. They are many times sweeter than natural sugar and as they contain no calories, they may be used to control weight and obesity. Extensive scientific research has demonstrated the safety of the six low-calorie sweeteners currently approved for use in foods in the U.S. and Europe (stevia, acesulfame-K, aspartame, neotame, saccharin and sucralose), if taken in acceptable quantities daily. There is some ongoing debate over whether artificial sweetener usage poses a health threat .This review article aims to cover thehealth benefits, and risks, of consuming artificial sweeteners, and discusses natural sweeteners which can be used as alternatives.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/25842566/

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Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a review of the literature summarizing the current knowledge and role in human disease.
A growing body of evidence indicates that Stevia rebaudiana Bertoni is protective against malignant conversion by inhibition of DNA replication in human cancer cell growth in vitro.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/29995279/

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Parkinson’s disease, renowned for its debilitating effects on movement, has always been intrinsically linked to the diminishment of dopamine, a chemical imperative for motor functions. However, a groundbreaking study by the University of Montreal divulges surprising revelations about the resilience of brain’s movement circuits even with a conspicuous deficiency in dopamine during the asymptomatic phases of Parkinson’s. This groundbreaking research, led by esteemed neuroscientist Louis-Éric Trude

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Some research papers conclude that stevia consumption can cause cancer due to DNA breakage and chromosome mutations. However, none of those studies are based on human subjects.
According to a study published in Oncotarget in 2018, steviol significantly limited the growth of human gastrointestinal cancer cells.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.bekarmic.com/blogs/knowledge-base/stevia-and-cancer-everything-about-stevia

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The use of steviol glycosides as non-caloric sweeteners has proven to be beneficial for patients with type 2 diabetes mellitus (T2D), obesity, and metabolic syndrome. However, recent data demonstrate that steviol and stevioside might act as glucocorticoid receptor (GR) agonists and thus correlate with adverse effects on metabolism. Herein, we evaluated the impact of steviol, steviol glycosides, and a Greek-derived stevia extract on a number of key steps of GR signaling cascade in peripheral blood mononuclear cells (PBMCs) and in Jurkat leukemia cells. #Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/28754349/

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Prostate cancer is the second most harmful disease in men worldwide and the number of cases is increasing. Therefore, new natural agents with anticancer potential should be examined and the response of existing therapeutic drugs must be enhanced. Stevia pilosa and Stevia eupatoria are two species that have been widely used in traditional medicine, but their effectiveness on cancer cells and their interaction with antineoplastic drugs have not been studied. The results indicate that SPME and SEME have an inhibitory effect on the viability and migration of prostate cancer cells and do not interfere with the enzalutamide anticancer effect. The data suggest that Stevia extracts may be a potential source of molecules for cancer treatment.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/32102219/

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Steviol glycosides are currently being used as natural sweeteners by the food industry and Stevia rebaudiana has long been used as a sweet plant in South America for patients suffering from diabetes. In this study, a Stevia rebaudiana ethanolic extract (SREE) was prepared, analysed and tested for antioxidant activity in terms of free radical scavenging properties and antiproliferative effects in cervix (HeLa), pancreatic (MiaPaCa-2) and colonic (HCT116) cancer cells. The antiproliferative mechanism was confirmed by testing the effects on cyclin D1-CDK4. #Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/27071804/

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Hydroponics offers a viable solution for obtaining plant products that are rich in micronutrients and ultramicronutrients, such as selenium. Selenium plays a crucial role in strengthening the body's immune defense and acts as a potent antioxidant. Low levels of selenium have been associated with an increased risk of heart attacks, strokes, and cancer. Stevia rebaudiana Bertoni (SrB), a relatively new crop in plant cultivation, was the focus of the present study. SrB has numerous medicinal and prophylactic properties, and its leaves are rich in macro- and microelements, vitamins, and diterpene glycosides.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/37522778/

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Stevia is unaffected by stomach acid, pancreatic enzymes and the process of digestion. It travels essentially “untouched” by the digestive process until it reaches the large intestine. There it “reacts” with the gut flora. It is then absorbed in the colon and travels to the liver. It is then bound to glucuronic acid via the glucuronidation pathway and eventually excreted through the urine. The glucuronidation pathway is a major liver pathway that detoxifies drugs, pollutants, estrogen, and steroids, etc.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://www.portalsalud.com/cuales-son-los-peligros-de-la-stevia_13092860/

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Bladder cancer (BC) is a global health issue that lacks effective treatment strategies. Growing evidence suggests that various natural products possess anti-tumour effects. This study aims to identify a novel agent that can be used in the treatment of BC.
Collectively, our data suggest that stevioside can be a potential agent for the treatment of BC.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/35820501/

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Scientists in China have developed a method to produce spider silk from genetically modified silkworms, offering a strong, sustainable alternative to synthetic fibers with applications in various industries. Researchers have synthesized spider silk from genetically modified silkworms, producing f

To whom it may concern.

Gustul ceaiului de kombucha diferă de la un producător la altul în funcție de metodele de preparare. Tocmai de aceea vă invităm să testați cele 8 sortimente iKombucha. După o experiență de peste 7 ani în producerea de kombucha, am adăugat la rețetele noastre stevia ca și îndulcitor, pentru ca produsul final să nu fie prea acru la gust pentru majoritatea clienților. Am dezvoltat 8 sortimente cu diferite arome, care să acopere înr-o anumită măsură gustul de ferment și să ofere gusturi plăcute.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://healthfully.com/stevia-and-cancer-5918164.html

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Stevioside is a diterpene glycoside found in the leaf of Stevia rebaudiana, a traditional oriental medicinal herb, which has been shown to have various biological and ethno-medicinal activities including antitumor activity. In this study, we investigated the effects of stevioside on the cytotoxicity, induction of apoptosis, and the putative pathways of its action in human breast cancer cells (MCF-7). For the analysis of apoptotic pathway, measurement of reactive oxygen species (ROS) and assessment of mitochondrial transmembrane potential (MTP) were achieved. We showed that stevioside was a potent inducer of apoptosis and it conveyed the apoptotic signal via intracellular ROS generation; thereby inducing change in MTP and induction of mitochondrial mediated apoptotic pathway. Taken together, our data indicated that stevioside induces the ROS-mediated mitochondrial permeability transition and results in the increased expression of apoptotic proteins such as Bax, Bcl-2 and Caspase-9. Effect of stevioside on stress-related transcription factors like NF-E2-related factor-2 opens up a new vista for further studies. This is the first report on the mechanism of the antibreast cancer (in vitro) activity of stevioside.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/23061910/

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A β-galactosidase from Kluyveromyces lactis was found to specifically catalyze hydrolysis of the glycosyl ester linkage of stevioside to yield steviolbioside, a rare sweetener that also exists in Stevia rebaudiana leaves. In a packed bed reactor, a reaction coupling separation was realized and a production yield of steviolbioside reached 90% in 6 h. The hydrolysis product steviolbioside presented higher cytoxicity on human normal cells (hepatocytes cell L02 and intestinal epithelial cell T84) than stevioside did. Comparing to the typical chemotherapy agent, 5-fluorouracil (5-FU), steviolbioside presents much lower cytotoxicity on all assayed human normal cells; it presented notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC-3. The remarkable inhibition on MDA-MB-231 cells makes steviolbioside a potential remedy for human breast cancer, when steviolbioside is served as a natural sweetener.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/26593477/

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Regarding nutritional benefits, the available studies, while numerous, do not provide proof that the consumption of artificial sweeteners as sugar substitutes is beneficial in terms of weight management, blood glucose regulation in diabetic subjects or the incidence of type 2 diabetes. Regarding nutritional risks (incidence of type 2 diabetes, habituation to sweetness in adults, cancers, etc.), it is not possible based on the available data to establish a link between the occurrence of these risks and the consumption of artificial sweeteners. However, some studies underline the need to improve knowledge of the links between intense sweeteners consumption and certain risks.
#Stevia #kombucha #ikombucha_ro #ikombucha
https://pubmed.ncbi.nlm.nih.gov/26430511/

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Researchers now hope to use the environmental engineering success to combat climate change.

Depression is not a gentle opponent, yet, forward-thinking studies and fresh advancements in technology have shed light on the way to triumph over this disease. In a new research study, there’s some positive news for the millions grappling with treatment-resistant depression (TRD). DBS (Deep Brain Stimulation) is beginning to show remarkable progress which seems to offer a ray of hope for the people who are suffering from debilitating Tourette’s syndrome. DBS, still an early stage trial, is a pr