this post was submitted on 23 Jun 2023
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Actual evidence from actual scientists.

[Image description: A patient holds bottles of medications for hormone replacement therapy as part of her gender-affirming care.]

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[โ€“] realChem@beehaw.org 14 points 1 year ago (1 children)

Exactly. Some things just can't be studied as part of a double blind RCT. For example, see: Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials

The perception that parachutes are a successful intervention is based largely on anecdotal evidence. Observational data have shown that their use is associated with morbidity and mortality, due to both failure of the intervention and iatrogenic complications...

The paper is funny, but the authors are making a serious point. RCTs are great when they're possible, but just because they're not possible doesn't mean we can't gather strong evidence anyway.

[โ€“] darq@kbin.social 5 points 1 year ago

Thank you for that paper, that's a great analogy honestly.