Counterpoint: in December of 1903, the New York Times ran an opinion piece saying that Man wouldn't unlock the secret of flight for at least a million years. 9 days later, the Wright brothers flew their first prototype airplane.
So, you know. Don't count out those hidden breakthroughs.
AGI, nanobots, fully autonomous self driving cars, cancer cures and aging cures, significant life extension, etc are all a long way off.
Few of these have really been proven possible, much less an expected time-frame.
AGI: We are no nearer to artificial self-awareness with LLMs and other approaches than when AI research began in the 1950s.
nanobots: We have the ability to print parts at that scale but material properties are very, very different at that scale. Heat dissipation is a real problem.
Fully autonomous self driving cars: This is a subset of no self-awareness in AI.
Cancer cures: Here is where I disagree. The progress in combating the thousands of individual types of cancer in the past 50 years is astounding and the pace is increasing.
Also factor in that more people end up needed treatment for cancer because a: they live longer and b: the massive reductions in other causes of death means more people who would have died in past generations from other things live long enough for cancer to develop.
aging cures: Quality of life as we age has improved greatly but
significant life extension: yes, it seems 120ish is hard coded as the terminal age and we still don't know if we can alter that.
SF is great in that it can show possible futures but it is not prediction.