This tip is super useful to me because not everyone is using a PC. On a PC sure, I would use the Home and End keys all the time. Now I'm using a laptop as my main computer and the Home and End keys are in a weird position that even to this day, 4ish years of laptop use, I still have to actually look at the keys to find them.

That's horrible for muscle memory, every time I switch desk/keyboard I have to re-learn the position of the home/end/delete/PgUp/PgDn keys.

I got used to Ctrl-a / Ctrl-e and it became second nature, my hands don't have to fish for extra keys, to the point that it becomes annoying when a program does not support that. Some map Ctrl-a to "Select all" so, for input fields where the selection is one line, I'd rather Ctrl-a then left/right to go to the beginning/end than fish for home/end, wherever they are.