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I would hope this is a good thing, because (as a layman) it sounds ludicrous to justify this suit using the 1st and 5th amendments. Hopefully the court agrees. Doubtful, but I'm naive.
They're grasping at straws. A majority of this court already ruled that Medicare has the right to compel vaccine mandates on providers who want Medicare reimbursements because Medicare has no obligation to do business with companies/providers that do not meet their rules. The Medicare statute is very clear here.
These companies are actually arguing that the government requiring negotiations violates their "free speech" to set their own prices and is "depriving them of life, liberty, or property" by not buying from them if they don't negotiate. The reality is that what they're asking the court to do is to compel the federal government to buy their products at the price they want to sell them at. The inevitable result of such an outcome is that they can charge 100x what they do now and there's nothing the government could do but spend 100x as much. When it's put like that, it's clear how absurd their argument is.
That makes sense. I worry that with how the courts are today, that they (Big Pharma) might win and - as you said - be able to charge even more for drugs, and there's nothing anyone can do but pay it.