this post was submitted on 19 Feb 2025
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Does anyone know how long (if it happens at all) are testicules irreversibly atrophied from HRT? Basically I'm scared that if I stop HRT they'll just go back to working the way they always have and I'm hoping that they won't.

I've been on HRT mono therapy for a year now and my testosterone has been nearly totally suppressed for the whole time, so I wonder if the girls are done for essentially...

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[–] dandelion@lemmy.blahaj.zone 14 points 2 days ago* (last edited 2 days ago)

I don't think there is such a thing, unfortunately. I think if you stop estrogen there is a good chance your testes will begin producing more testosterone again.

There are people who after years of taking estrogen stop and are fertile again. Sometimes people are not able to be fertile again, but my point is that you can't count on testicular atrophy to be permanent.

If you want that kind of guarantee I would look into having the testes removed with an orchiectomy, which is a much cheaper and easier surgery to recover from than a vaginoplasty, and which would guarantee your body will permanently be unable to produce large amounts of testosterone.