this post was submitted on 27 Jan 2024
275 points (98.9% liked)

Asklemmy

43952 readers
700 users here now

A loosely moderated place to ask open-ended questions

Search asklemmy ๐Ÿ”

If your post meets the following criteria, it's welcome here!

  1. Open-ended question
  2. Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
  3. Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
  4. Not ad nauseam inducing: please make sure it is a question that would be new to most members
  5. An actual topic of discussion

Looking for support?

Looking for a community?

~Icon~ ~by~ ~@Double_A@discuss.tchncs.de~

founded 5 years ago
MODERATORS
 

I often hear, "You should never cheap out on a good office chair, shoes, underpants, backpack etc.." but what are some items that you would feel OK to cheap out on?

This can by anything from items such as: expensive clothing brands to general groceries.

you are viewing a single comment's thread
view the rest of the comments
[โ€“] Cinner@lemmy.world 1 points 10 months ago* (last edited 10 months ago)

As someone who takes Adderall daily and has for many years, I can tell you the Teva brand generics work very well while the malinkrokdt (sp?) in the same dosage do almost nothing, and I crash very fast and need a nap in the afternoon and have to go to sleep early.

Conversely, I got some random Indian-HQ brand from Walmart many years ago (a pink tablet) that kept me up for 3 days. I was begging God for sleep. Placebo or nocebo my ass. Pretty sure someone "accidently" added a methyl group and was overly gracious with the dosage.

The book Bottle Of Lies goes into this much deeper. https://www.npr.org/sections/health-shots/2019/05/12/722216512/bottle-of-lies-exposes-the-dark-side-of-the-generic-drug-boom

But it's also noticable in OTC meds. If you get real, severe inflammatory pain (not 'oh I have le headache'), buy a bottle of ibuprofen from the local dollar store and then buy brand-name Ibuprofen from a big box store, and blind test yourself.

(I may be misremembering the specifics on this part) Generics can only be 80% similar to the brand name in formulation, and often times they use fillers and binders that aren't as good as the formulation created by the R&D department of PharmaCo.

I'm not saying generics do nothing, I'm just saying my boss asks me what's wrong when I can't get my Tevas filled and have to use another manufacturer.