this post was submitted on 25 Feb 2024
507 points (90.6% liked)

Cool Guides

4702 readers
1 users here now

Rules for Posting Guides on Our Community

1. Defining a Guide Guides are comprehensive reference materials, how-tos, or comparison tables. A guide must be well-organized both in content and layout. Information should be easily accessible without unnecessary navigation. Guides can include flowcharts, step-by-step instructions, or visual references that compare different elements side by side.

2. Infographic Guidelines Infographics are permitted if they are educational and informative. They should aim to convey complex information visually and clearly. However, infographics that primarily serve as visual essays without structured guidance will be subject to removal.

3. Grey Area Moderators may use discretion when deciding to remove posts. If in doubt, message us or use downvotes for content you find inappropriate.

4. Source Attribution If you know the original source of a guide, share it in the comments to credit the creators.

5. Diverse Content To keep our community engaging, avoid saturating the feed with similar topics. Excessive posts on a single topic may be moderated to maintain diversity.

6. Verify in Comments Always check the comments for additional insights or corrections. Moderators rely on community expertise for accuracy.

Community Guidelines

By following these rules, we can maintain a diverse and informative community. If you have any questions or concerns, feel free to reach out to the moderators. Thank you for contributing responsibly!

founded 2 years ago
MODERATORS
JCSpark@lemmy.ca
507
The lethal doses of 55 substances (infosec.pub)
submitted 9 months ago by Ninjazzon@infosec.pub to c/coolguides@lemmy.ca
160 comments fedilink hide all child comments
 
you are viewing a single comment's thread
view the rest of the comments
[–] Taniwha420@lemmy.world 6 points 9 months ago (2 children)

Yes, I came here for this conversation. What's the ratio of effective dose to LD50 again, because that's typically what matters. That's where cannabis and ethanol are in totally different categories. And how high do you need to get before dying from LSD?

[–] Pipoca@lemmy.world 4 points 9 months ago (1 children)

16.5 mg is 16500 μg. So a 70kg person would need over 1 million μg.

According to https://www.trippingly.net/lsd/the-lsd-dosage-guide, 25 μg is where visual effects start.

700 to 1000 μg. Full out-of-body experiences. Synesthesia more likely. Religious imagery often strong. Entire loss of rationality, lack of ability to walk or interact in any meaningful way.

1500 μgs+ Experiences may be similar to DMT but extended. Basic body functions are challenging. Vision is consumed by hallucinations. No sense of self remains. Audio hallucinations may be strong. Standard reality no longer applies. Merging with objects likely. No type of rational thought left.

A deadly dose is around 800x higher than that. You wouldn't be as high as a kite. You'd be as high as Voyager one.

[–] smegforbrains@lemmy.ml 3 points 9 months ago

The data about LSD lethality in humans is sparse at best it seems: https://www.healthline.com/health/substance-use/can-you-overdose-on-lsd#risk-of-death

[–] sicarius@lemmy.world 2 points 9 months ago

That dose of 16.5mg/kg ld50 is for rats.
Mice is lower at 0.3mg/kg.
There have been no know deaths from humans overdosing on lsd, even when people have taken ridiculously high amounts by mistaking it for cocaine and railing lines of it up their nose.
Sure, a little coma, hypERthermia and light gastric bleeding but nothing a short stint in the hospital didn't sort em out with no lasting effects.