this post was submitted on 25 Feb 2024
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[–] pearsaltchocolatebar@discuss.online 45 points 9 months ago (2 children)

They don't specify the route of administration, so none of these numbers are worth anything.

[–] ExfilBravo@lemmy.world 7 points 9 months ago (2 children)

I was going to say I smoke/eat more than 1200mg of THC a day and I'm not dead yet (yes I have a problem and yes it's expensive).

[–] pftbest@sh.itjust.works 28 points 9 months ago (2 children)

This is per kilogram of your mass. So if your weight is 80kg then the lethal dose would be 96000mg not 1200. At least that's how I understand this.

[–] original_reader@lemm.ee 3 points 9 months ago (2 children)

So that means 7.2 litres of water to kill an 80 kg human. That's a lot of water to down in one short sitting.

Not easy to do. Fortunately.

[–] Chekhovs_Gun@lemmy.world 3 points 9 months ago

Back in college, there was this thing called the "4, 4, 40 challenge" where one would have to drink 4 liters of water, in 4 minutes and hold it down for 40 secs. Lots of vomiting would ensue.

[–] kinsnik@lemmy.world 1 points 9 months ago

So that means 7.2 litres of water to kill an 80 kg human

well, not exactly. since this is the LD50, drinking 7.2 liters of water would kill about half of the population that try. the other half would survive

[–] Pipoca@lemmy.world 3 points 9 months ago

More than 1200 mg of pure THC, or 1200mg of cannabis leaves?

Those aren't even remotely the same thing, in the same way that 12oz of beer and 12oz of everclear are very different, or 1g of pure nicotine is very different than 1g of tobacco leaves.

Not to mention, LD50 is about a single dose. There's a big difference between taking one shot an hour for 16 hours straight, and chugging 16 shots in one go.

[–] SorryQuick@lemmy.ca 3 points 9 months ago

Looking at the wikipedia page for some of those, it seems to be intravenously. For example, Botox (the last one): “A toxin is 1.3–2.1 ng/kg intravenously or intramuscularly, 10–13 ng/kg when inhaled, or 1000 ng/kg when taken by mouth”