this post was submitted on 04 Aug 2026
13 points (100.0% liked)

Transfem

5735 readers
133 users here now

A community for transfeminine people and experiences.

This is a supportive community for all transfeminine or questioning people. Anyone is welcome to participate in this community but disrupting the safety of this space for trans feminine people is unacceptable and will result in moderator action.

Debate surrounding transgender rights or acceptance will result in an immediate ban.

This community is supportive of DIY HRT. Unsolicited medical advice or caution being given to people on DIY will result in moderator action.

Posters may express that they are looking for responses and support from groups with certain experiences (eg. trans people, trans people with supportive parents, trans parents.). Please respect those requests and be mindful that your experience may differ from others here.

Some helpful links:

Support Hotlines:

founded 3 years ago
MODERATORS
 

Hey, I just started my SSRI (Sertraline), because I needed that I was feeling terrible last week.

To be honest it's been 2 days since I took Sertraline and somehow I feel wired in a weird way. Like I have too much energy but not in a manic way.

At least I'm feeling good. It's weird I didn't expect the effects to start that fast and expected to feel empty.. Anyway, the effects will most likely stabilise. But here's my main issue. My libido has dropped immensely. That and I've barely slept, too much energy last night I hope tonight will be better.

To be more explicit, let's say the anticipation has stayed the same but the effect of being touched has dropped like 90-95% on pleasure. I barely feel anything which is quite annoying and at some point the anticipation will just lower too because there will be a difference between what I expect and got. Like my tits used to be so sensitive and now it feels like pre-hrt level (which honestly I'd rather not it to stay like this I hate it.) I'm finally with a person I love physically and it feels bad that my body doesn't respond the same.

My question basically is : Will it come back when my body adapts to the SSRI? Have anyone had a similar experience?

you are viewing a single comment's thread
view the rest of the comments
[–] That_Bitch_Is_Cily@lemmy.blahaj.zone 2 points 1 week ago (1 children)

Hi! I was on Sertraline for several years. I started at 25mg a day and slowly ramped up to 125. It was way before I transitioned so I can't speak to any changes I felt due to HRT. I feel like it helped me round out the peaks and valleys of my anxiety and depression so that I could at least function and try to institute some positive coping strategies without cratering into a puddle of depressive goo. I had several weeks of onset where it just felt like I was literally floating and extremely disassociated. This subsided as time went on but would come back if I ever missed a dose.

Libido wise, it didn't really effect my desire too much. It helps that my wife was a smoke show (still is but used to be too), but I understand what you mean when you say the sensation has dropped. I sometimes wouldn't be able to orgasm for hours. Overall, I think you definitely need to wait for it to normalize in your system before you can really notice the effects of the sertraline specifically. I haven't been on it for a long time but I think like some of what you're experiencing could also be due to HRT. In my experience, that initial onset was so wacky that it's hard to pin anything down as being specifically caused by the medicine. Hope this helps :)

[–] Shirow@lemmy.zip 2 points 1 week ago (1 children)

Honestly it is not hrt that stopped me being sensitive there and other things. I just knew how my body reacted to the touch, the feeling that radiates through my chest and belly too sometimes. And that feeling dimmed way too much from the day before taking sertraline to a few hours later starting it.

I also asked my GP if upping the dose is a good idea I'm not sure if what I'm feeling is akathisia too because I don't remember how I felt pre depression level. But I feel restless and jittery nonetheless

You know your body better than I do. But I just think that a couple days is way too early to notice or be concerned about any long term changes or consider changing doses. It takes weeks for the medicine to equalize in your system. That being said, sertraline and SSRI's in general have a well known side effect of diminished libido.